P – Patient, Population, or problem

Hemodialysis patients in chronic dialysis facility at risk of Hepatitis B infection. 

I-Intervention, Prognostic Factor, or Exposure

Initial hemodialysis admission laboratory testing of HBs Ag, HBsAb, HBs Core Ab. Administration of HBV series (Engerix B or Recombivax) as soon as HBs Ab result of less than 10 mIU/ml. obtained. 

C- Comparison or Intervention

The result of HBsAb conversion on pre-dialysis patient administration of HBV and initial hemodialysis admission administration of HBV.

O- Outcome you would like to measure and achieved.

The number of patients with HBs Ab conversion after the HBV series.

Hemodialysis patients are all at high risk of Hepatitis B infection since they are exposed to blood in dialysis unit and being immunocompromized. CDC requirements in all hemodialysis patients are to receive HBV if  HBs AB is less than 10 mIU/ml.
It is very important for me in my clinical practice to know how to interpret the Hepatitis B laboratory result and the HBV schedules in order to provide timely administration of HBV to every hemodialysis patients that are susceptible to hepatitis B infection.